Maddie runs a Daycare Service at the Tipton, and when Maddie has a family obligation to attend to, Zack and Cody take over. Meanwhile, London encourages Mr. Moseby to take yoga to help him relax a bit more.

Zack and Cody have to repair a wall that they damaged as punishment. London begins attending Maddie's private Catholic school due to her poor grades.

Zack makes a new rich friend, who is mean to Cody and thinks he is a dork. Maddie and London have to do a parenting project for school as partners.

Zack and Cody go on a double date to a miniature golf course. Zack tries to impress his date, Ella, but things backfire on him. Cody and his date, Barbara Brownstein, have an intellectual attraction. London joins a bookclub with her rich friends much to Maddie's amazement. Carey tries to become a more healthy-living person.

Zack tries out for the high school basketball team but realizes there's some stiff competition, the kind he didn't face in middle school, and worse yet, the giant, in-your-face Coach Little (Michael Clarke Duncan). Meanwhile, when they're rejected as cheerleaders, Cody and London form their own cheerleading squad with the help of Mr. Moseby.