Clark finds himself up against Lex when he befriends Victor Stone, a half-machine, half-human subject who escapes from LuthorCorp with the aid of a sympathetic doctor.

After escaping from the Phantom Zone, Raya comes to Smallville to visit Clark. Raya and Clark grow close, and Raya reveals how to repair the Fortress of Solitude. Unfortunately, Baern, another escapee seeks out revenge on Clark and Raya for his time spent in the Zone.

Clark is once again exposed to red kryptonite, and his "other self" goes on a rampage of sorts on Valentine's Day, kissing the women he's most attracted to and expressing his uninhibited feelings for the various relationships around him.

Clark hears his mother's voice trapped in Kara's crystal, and releases her. She gives him Jor-El's ring made of Blue Kryptonite, which strips him of his powers.

Lionel has Clark kidnapped, and when Chloe and Lana confront him, he makes them think Lex is the culprit. Chloe and Lana then beg Jor-El to restore Kara's memory because she's the only person who can rescue Clark.

A heartbroken psychotic wearing a watch jeweled with kryptonite abducts Chloe and Jimmy and subjects them to a polygraph; while searching for them, Clark and Lois pose as a couple.

The Persuader attacks Clark; Chloe, as Brainiac, tells Davis he is Doomsday and that he was created to destroy the "other Kryptonian" and the world.

Linda Lake returns to Metropolis and threatens to expose Clark’s secret unless he promises to give her exclusive information on the red-blue blur so she can become a star reporter again. Refusing to be blackmailed, Clark tells Lois his secret and asks her to write his story for The Daily Planet.

DC Comics’ “The Wonder Twins” Zan and Jayna show up in Metropolis to help The Blur fight crime but end up botching several rescues, landing Clark in hot water with the District Attorney’s office.

A man named Sylvester Pemberton tracks down Chloe and tells her he knows about her team of superheroes and needs their help. However, before he can explain who he is, he is attacked and killed by Icicle. Clark and Chloe's investigation leads Clark to the former headquarters of the Justice Society of America where he meets up with Nelson AKA Dr. Fate, Carter Hall AKA Hawkman and Courtney AKA Star Girl. Courtney pleads with Hawkman and Dr. Fate to help her catch the killer that is targeting their group but they are reluctant to resume their duties as superheroes. Clark, John Jones, Green Arrow and Chloe team up to help the JSA stop Icicle before he murders another member of the group. Meanwhile, Lois receives a package from a mysterious agency called Checkmate, run by Amanda Waller.

Much to Clark's surprise, Martha Kent returns to Smallville with her new boyfriend, Perry White in tow. Lois and Perry realize they are both working on the same story about the Red Queen, and decide to team up, which ultimately puts them in serious danger. Chloe helps Clark search for the Book of Rao, which they believe contains information on how to stop Zod and his army.

After Lois departs for Egypt, the Daily Planet hires a new reporter by the name of Cat Grant to take her place. An assassin named Deadshot takes aim at Cat but Clark learns the man has a dangerous hidden agenda that involves The Blur. Meanwhile, Carter Hall turns up in Egypt to keep an eye on Lois and he tells Lois about his wife Shayera.