After the body of Lois Romney is found in a hotel room, Goren and Eames link her to Dale Van Acker, a junkie and the son of wealthy scion Priscilla Van Acker. Van Acker strongly disapproved of her son's pregnant fiancée, which leads Goren and Eames to suspect she may have wanted to get rid of the girl on a permanent basis.

When a European con man is found beaten to death, the detectives look for the investors he swindled, learning quickly that the man also had relations with their wives.

The detectives investigate a slain bank robber and check out his sister, who is involved with a bogus United Nations economist. As the detectives close in on the suspect, Goren learns the suspect wants his children's approval and must stop him before any more murders.

When the murder of a city auditor and his family seems too perfect, Goren and Eames turn their attention towards law enforcement personnel after learning that the auditor was investigating a number of former cops upon suspicion of double-dipping.

The double murder of a social services worker and a deputy mayor lead the detectives to suspect a couple who may have a grudge against the social worker for taking away their children. When they learn that the social worker had taken special interest in a child prodigy being considered for admission to a prestigious, accelerated school, they examine both the boy and his obsessive father.

The detectives are called to investigate the adult daughter of a retired officer which takes them to a case of terrorism involving someone she knew that includes a shipment of explosives.

The murder of a woman in her apartment results in her son, recently paroled after serving 15 years for murder, becoming the prime suspect. Having consulted with the lead detective on the old case, Goren and Eames discover he was involved in a cover-up to rush other cases to closure.

Santeria cultists kill the son of a women that believed from them she had psychic powers.

The bludgeoning of a rich family patriarch has the detectives investigating several suspects, each with their own motives: his estranged wife whom he was about to divorce, a male friend of hers who was a parolee, their childrens' nanny, the victim's brother in law who is a doctor, even the oldest son. Goren and Carver call the family of suspects together to sort it all out... in family court.

A man commits fraud, forgery, and murder to discredit the organization that took advantage of his mentally ill mother, impoverished his family, and ruined his childhood.

The investigation into the death of a woman searching for the whereabouts of her late mother's antique ring leads Goren and Eames to a physician serial killer who has cleverly concealed the murder of over two hundred of his patients.

When city health inspector Larry Chapel is found dead in an elevator, a quick look into Chapel's home life introduces them to Chapel's recently widowed brother, Evan, and little girl Gwen. Goren isn't very surprised to learn that Nicole Wallace is Evan's fiancée and the future mother to his little girl, but Major Case soon realizes they're off the mark in who they believe the suspect is, and Goren's only hope is to get Nicole to help him trap the killer. Logan joins the Major Case squad, but isn't pleased with being relegated to the background while the other detectives solve the cases, and Deakins tries to find a partner for him.

After Russ Corbett and his wife are found in a seedy hotel room, Russ dead of an overdose, Eames and Goren follow the trail of evidence to Bernard Fremont, a professional partier. With his beautiful blonde companions, Fremont insinuates himself into the lives of couples who don't know the city very well, then robs them blind. While investigating Fremont's past in Asia, Goren realises that he is the mastermind that turned Nicole Wallace into a murderer, and his most successful pupil.

Barek and Logan investigate when the deaths of two young girls seem to be connected to a voodoo-practicing nurse. Things turn interesting when it seems the young woman has placed a voodoo curse on Logan.