Greene assists paramedics in treating injured children at a school bus accident. En route, Doug and Jeanie survive their own accident. Kerry stops Doug from treating Jeanie...or any other patient. Doug decides to resign and leave Chicago for the Northwest and asks Carol to come with him. She decides against it, but he leaves anyway. Carol steps down from running the clinic so that Anspaugh will keep it open. Jeanie discovers she may have contracted hepatitis. Hospital janitor Mobalage's wife is stabbed.

Hathaway befriends an out-of-work waitress, Meg. Seven-months pregnant, Meg cannot afford prenatal care. Hathaway invites her to the hospital, performs free tests and helps her interview for a job in the cafeteria.

Greene returns to work but confuses words and displays uncharacteristic anger. Eager to get out of his per diem situation, Benton agrees to a full time position. Carter visits his cousin, who became paralyzed after a drug overdose. A workplace disaster results in numerous injuries and fatalities among illegal immigrants.

The ER is flooded with foster care home residents, attacked by a shooter bent on tracking down his son, who , with the help of Dr. Green, was put into the foster care system amid allegations he was being abused by his father.