Even though he suffers from intense pain due to his stabbing injuries, Carter returns to work and prescribes a controversial procedure for a suicidal patient. Greene tries to convince his father to undergo cancer treatment.

Corday rushes through a surgical procedure in order to take off on a romantic weekend with Greene. She is later called back to the hospital after her patient suffers complications. Abby's mother, Maggie, who suffers from bipolar disorder (manic-depressive) and refuses to take her medication, unexpectedly visits Abby at the hospital and wreaks havoc on Abby's life.