The ER treats victims of a gang shootout. Carter arrives late and unprepared for his new position. Mark learns all about being an attending, including senior staff's habit of bad-mouthing the residents, particularly Doug Ross. Mark hires a new chief resident, Kerry Weaver. New third year med students arrive to complete their ER rotation.

Kerry Weaver manages to offend just about everyone in her first day as chief resident. Carol goes on a ride-along with paramedics Shep and Raul, sharing a ferris wheel ride with Shep. Peter and Jeanie's secret relationship comes to a head. Susan is stuck caring for Little Susie while Chloe attends school. Dr. Ross has his hands full with a young pyromaniac. Carter shows interest in med student Harper Tracy.

Carter gets his first patient...and loses him. Susan's feud with Kerry Weaver intensifies when Weaver demands all of Susan's procedures be cleared with her. Chloe abandons Little Susie again for a lucrative career in the flea market business. Carol finishes her paramedic recertification by picking up a very overweight, lethargic man. Shep hits on Carol. Jeanie ends her relationship with Benton. Wendy conducts interviews with various ER staffers for an article on Dr. Greene. Dr. Ross cares for a four-year-old Asian boy with AIDS.

Weaver and Susan's feud escalates to the point where Mark needs to step in and fix it. Benton is involved in a parking lot altercation, resulting in a broken hand and Carter replacing him in surgery. Mark cares for an abandoned elderly woman. Susan tries to juggle her work and care for Little Susie. Shep risks his life to bring in a gunshot victim.

Shep and Raul bring a dozen malnourished and abandoned children into the ER, keeping everyone very busy. Shep has a run-in with Malik and Benton when he makes an off-handed racially insensitive remark. Carter's high from the admission of Mrs. Rubadoux to the study ends when she shows no signs of recovery. Jeanie and Carol clash when Jeanie receives a poor evaluation. Al asks Jeanie to give him another chance. Mark is served with divorce papers.

Shep and Raul respond to a massive fire without proper equipment, risking their lives to save addicts and their children. Shep will be okay, but Raul has third-degree burns covering his body; it's only a matter of time. The ER is flooded with burn victims. Chloe returns to Chicago. Doug is stood up by his father for a basketball game.