Ed falls for a girl he meets after hearing her playing the piano in a bar in Las Vegas. While they are out together Ed is knocked unconscious and the girl disappears. Ed, Ironside and the team try to figure out the mysterious circumstances behind her disappearance.

A compulsive (and unlucky) gambler is in debt to a local mobster for $32,000. Ironside wants to put the mobster away, but only can if the gambler is prepared to turn state's evidence. The Chief has to persuade him to turn against the man who is offering him a way out of debt. (NB - The second episode to feature original song From The Day You're Born.)