An obnoxious talk show host known as ""The Peoples' Voice"" begins to receive death threats, and the Chief is assigned to protect him. Firstly he must overcome his own feelings of dislike for the man, but are those feelings entirely misplaced? Events escalate when the host's wife is killed by a car bomb apparently meant for her husband.

An old friend of the Chief's, recently widowed, is hearing strange voices and receiving threatening 'phone calls. She is afraid that she is going mad, but the Chief is determined to prove that this is just what somebody wants her to think.

Barbara Jones, the amnesiac victim with whom the Chief once fell in love (season one episode Barbara Who), calls Ironside in when her daughter is kidnapped. Not only is it a difficult case, but the Chief has an over eager Sheriff, a jealous husband and his own feelings to contend with, as he attempts to find the girl before it is too late.

When a lowlife bookie is found severely beaten, five witnesses identify Ed as his attacker. Unable to provide an alibi, Ed finds himself having to prove his own innocence; and when the victim dies and Ed is arrested on a murder charge, the team have to find out who the real killer is.

The Chief attends his high school reunion, only to find two of his old classmates recently murdered, and somebody apparently after his own neck. With Ed and Fran to help him, he searches for some clues, which soon prove to be leading him back to the accidental death of another old friend in 1940.