Two killers break out of their cell in the precinct and hold Ironside and Eve Whitfield hostage, forcing the Chief to come up with a fool-proof plan for their escape. As always Ironside has a trick or two of his own up his sleeve.

Ironside is the only witness to a murder, but has to go into hospital for exploratory surgery immediately after the events that he witnessed. The murderer is determined that he should not leave hospital alive, and as the Chief deals with the possibility of maybe one day being able to walk again, his presence in the hospital helps various other citizens right wrongs in their lives. Meanwhile Ed, Eve and Mark deal with their own worries and fears for the Chief as the murder attempts escalate.

Ed goes to LA to fetch a prisoner, but when confronted by a pair of hostile beat cops after a mugging, he loses his cool and ends up in the County Jail. Caught up in a blatantly unfair system, he begins to doubt his own integrity as a representative of a law that is clearly failing so many people; and refuses to allow the Chief to bail him out.

The Chief is in the bank when it is robbed by a gang of three men, planning to await the arrival of a payroll delivery truck. The threesome are at odds with each other from the start, and Ironside plans to work on the antagonism between them, but they are wise to his plans and will stop at nothing to get what they want.