The three interns are each assigned patients with various illnesses. Statistically speaking, one of the three is going to die. J.D.'s patient is 86 year old Mrs. Tanner, who is in renal failure. 20 year old David Morrison is Turk's hernia patient and Elliot's patient Mrs. Guerrero only speaks Spanish and might have lupus.

Dr. Cox is still facing the threat of suspension, and coincidentally, J.D. is assigned to a special patient: Jordan Sullivan, an important board member. She is very demanding and J.D. ends up sleeping with her after he confronts her. Only he didn't know that she is Dr. Cox's ex-wife, and now the only one who can save J.D.'s mentor from being fired by the evil Dr. Kelso. Meanwhile, Elliot is assigned to take care of a shrink whose jaw has been wired shut, and for whom she ends up becoming a patient. Carla's mom makes a scandal after Turk spends the night at Carla's, and when she breaks her leg, Carla blames Turk for it.

A woman slips and falls on the wet floor of the hospital. Afraid that she might sue the hospital, Dr. Kelso asks J.D. to stand by her and be friendly, so she won't sue them. But J.D. is very busy with Dr. Cox's 24-hour marathon to keep his ICU patients alive.

Elliot is desperate for some attention from Dr. Cox. Meanwhile, Turk snaps at Carla when she steals fries from his plate.

Alex and Elliot argue over missing medication, and J.D. needs to choose sides.

Meanwhile, Dr. Kelso gives Carla a ride to work and she sees a totally different side of him. Turk develops a conflict with Dr. Cox after he finds out that Dr. Cox has secret feelings for Carla.

J.D. fears being contaminated with Hepatitis B, after a needle accidentally sticks his forearm.

Meanwhile, Elliot has a hard time combining her new relationship and keeping up with studies. Turk obsesses about getting in shape, after Carla makes a fat joke about him.

Elliot sleeps with a handsome doctor she hardly knew and soon becomes the hospital tramp. Turk suffers from his back after operating with Dr. Amato, a very short surgeon. J.D. finds out that wearing a white coat doesn't make him a better doctor, but is upset by having Dr. Cox throw in his face that he made another mistake. And Dr. Kelso is just dying for an opportunity to lash out his anger on Dr. Cox.

J.D. and Turk think they've got bad karma after hitting a car and causing an accident, while playing golf on the hospital roof. Dr. Cox bends over backwards to give Jordan as much comfort as possible on her labor day, and she confesses to J.D. that Dr. Cox is the real father. Elliot seeks advice from Carla on how to tell Paul that she's crazy, because they're getting more intimate and she can't hide it anymore. But Carla is feeling too crazy herself with the upcoming wedding.

A personal secret of Dr. Cox is revealed during hospital visitations by a cocky MD (Jay Mohr), who establishes a rapport with J.D.

Dan decides to stay with J.D. for a while after their mom's new fiancé kicks him out, but after spending some quality time with him at the hospital, Dan isn't sure if he likes the cynical person his little brother has become.

Elliot tries to deal with her own problems of a long distance relationship and decides to try moonlighting as a pet examiner with Carla to save up money.

A chance meeting in the elevator sparks a new friendship between J.D. and the mysterious Danni whose ongoing dialogue about her ex forces J.D. to talk about his feelings for Elliot.

Carla's brother Marco comes to visit, but he still hasn't forgiven Turk for mistaking him for a valet at their mother's funeral. Unfortunately, Turk can't even apologize because Marco can't speak anything but Spanish.

At the hospital, Dr. Cox relishes his new job promotion but is surprised when J.D. doesn't follow his lead in contradicting Dr. Kelso's orders.