Lucy learns a hard earned lesson about what it takes to be a doctor. Meanwhile J.D. and Turk spot a potential love connection between Denise and the new med student, Drew, as they play matchmakers with a little bit of help from Dr. Kelso.
J.D. still clamors for Dr. Turk's approval as he approaches his final day of teaching at Sacred Heart, Lucy searches within herself for the courage to perform a basic medical procedure on a real human, and Denise and Drew make things official.
The med students of Winston University finally find something to be thankful for when Cole identifies his true calling in surgery, Drew finds the love of his life, and Lucy finds the inspiration to become a doctor.