After Ruthie's boyfriend Peter grows more suspicious of his mother's new fiancé, Reverend Camden steps in to counsel the threesome and get to the root of their problems. Meanwhile, Chandler provides pre-marital counseling to a couple who don't seem destined for the altar; Cecilia confides to Simon the reason she doesn't want her parents to renew their wedding vows; and Roxanne tries to convince Chandler to return home to see his dying father.

The Camdens, especially Lucy and Ruthie, grow concerned that an unusually joyful Annie isn't dealing with her true emotions following the death of her father Charles, but the happiness proves to be infectious as it soon spreads through the family and all over town. Meanwhile, Eric tries to convince an unhappy Chandler that he should consider adoption. At the same time Chandler is approached by a mysterious young girl who gives him a cryptic message before she disappears.

When Simon and his new girlfriend Rose (guest-star Sarah Thompson), make an unexpected visit to Glenoak to meet their respective parents, Annie begins to suspect their relationship might be on a fast track. She let's them know they are not allowed to sleep in the same room together in the house as they spend the night. Rose puts up a fight with both Annie and Simon over the sleeping arrangements, but eventually take will. Meanwhile, Eric hides the news of Mary's (Jessica Biel, who does not appear in the episode) divorce, worried that it will most certainly break Annie's heart.

Also, Martin becomes the third wheel again in Ruthie and Vincent's relationship as Ruthie thinks Martin is jealous of their relationship despite the fact that Vincent wants Martin to convince Ruthie to dump him. The adoption process for George (guest-star Brad Maule) and his wife over the Davis children becomes more complicated when their biological mother fights for the adoption process to not happen. Lastly, Ma