As Dana's upcoming birthday makes her decide to seek a volunteer sperm donor so that she can have a child, she is confronted with a newborn who is HIV-positive. Lu is accused by an enraged mother of being responsible for her teenage daughter's sexually-transmitted disease because Lu provided the girl with birth control.

A teenage cancer patient refuses to continue chemotherapy, Dana makes preparations for what she assumes will be her forthcoming pregnancy, and Lu finds herself in the middle when she suspects abuse in a family.

Hospital executives approach Dana to perform a risky procedure to save an unborn child's life; Lu treats a prison inmate for cervical cancer and decides to take on the prison system in regard to women's health care.

Also Dana becomes emotionally distraught after her pregnancy ends. Lu tries to stop a patient from utilizing an expensive screening test not covered by the clinic to save the patient's money. And Lu fears an elderly patient may be stashing enough medication for a suicide attempt.