Lu coaches a teenage basketball team and is troubled when a player faints at a game. She later finds traces of steroids in her blood and wonders if the entire team is on the drugs. Dana is mystified when a complete stranger shows up in the ER with Dana's name and phone number in her purse. Dana must make a difficult decision for the women and regrets that she can't find her family so they can decide.

Lu (Rosa Blasi) and Dana (Janine Turner) intervene when a woman with a controversial bone and muscle disease is denied her disability claim. And Dana gets in the middle of an immigration dispute when she finds out that the physical damage on a 15-year-old sexual assault victim was actually inflicted by the girl's parents.

Andy goes beyond the call of duty to expedite the Food and Drug Administration's approval of a drug that could help Robert's wife, who has multiple sclerosis. Also, Andy intervenes when a family is accused of endangering the life of their young daughter. Meanwhile, a woman with terminal lung cancer claims to be Lu's half-sister.