Mindy isn't getting respect from Danny and Jeremy, so she goes off to experience life as her own boss. Meanwhile, the group fights back when they discover that holistic midwives are stealing patients from Shulman & Associates.

Tax troubles inspire Mindy tries to rekindle a phony relationship with Cliff.

Mindy has made up her mind to move to San Francisco and start a practice with Rob, but her credit history jeopardizes their ability to get a loan. Meanwhile, Danny tries to let the office know that he is moving to San Francisco with Mindy, but they're convinced his "big news" is something completely different.

When Mindy's fertility practice faces financial trouble, she finds herself forced to take on an unlikely business partner.

While Mindy struggles to take care of a sick Leo, Shulman & Associates is rocked by a nurses’ strike led by Ben, a handsome male nurse. Meanwhile, Jody tries to sell the upstairs apartment and Brendan Deslaurier comes to Mindy seeking help.

Shulman and Associates is turned upside down when Mindy hires a down-on-his-luck Brendan Deslaurier. Meanwhile, rumours fly about who's the father of Tamra's baby.

Mindy’s fertility practice is in danger and Annette’s upcoming surgery looms large. While Mindy and Danny wait for word on the surgery, Mindy attends Morgan and Tamra’s dream wedding, where she and the rest of the Shulman gang try to find their own happy endings.