A routine surgical procedure goes awry when Alex's patient, a soon-to-be-wed young woman, falls into a coma. While Alex struggles with a case that hits close to home, Joel treats a patient who does his own body modifications, and Charlie finds himself drawn to Alex's coma patient in the spirit world.

Alex is surprised twice in one night – first when she realizes she's been tricked into a blind double date, and again when she has to rush her mystery man to the ER.

Alex and Maggie perform an intricate procedure; Joel thinks his dad is hiding something; Charlie suspects foul-play when he sees a boy and his grandmother.

A young motocross rider is diagnosed with Leukemia, forcing Dr. Alex Reid to navigate family secrets in order to put her young patient on the road to recovery.

Charlie decides to go a day without using his special abilities; Alex organizes a trip to Dana's cabin; Zach takes control of a life and death situation involving Dawn's college roommate.