When Joel gets cold feet in the OR, Kinney takes him with her on a Continuing Medical Education assignment in her hometown to help clear his head. During their field trip, a woman gets pinned underneath a truck and Joel and Kinney lead the rescue effort. Meanwhile, Charlie meets a newly deceased therapist who suspects it’s an emotional block that is keeping him in his coma. Encouraged by Charlie breathing on his own, Alex continues her rounds and diagnoses a fitness buff with a rare condition.

Shahir and Alex attempt a radical surgery on an Alzheimer's patient; Tom discovers his mentor is keeping a secret; Charlie is torn between Dawn's wishes and the final requests of a dead con-man.

Alex struggles with being a mom, a surgeon and now mentoring a junior resident.

Faced with a chef who refuses treatment, Alex is forced to confront how she feels about Dana's methods.

Alex and Cassie try to free a young woman from her abusive partner; a patient's pacemaker malfunctions.