In the premiere episode, the Chief of Surgery ends up in a coma, and his fiancée and fellow surgeons fight to save his life.

Alex Reid treats a young boy with mysterious symptoms while dealing with the arrival of Charlie's ex-wife. Elsewhere in the hospital, Joel Goran and Maggie Lin try to help a patient who refuses life-saving treatment on religious grounds.

After Charlie’s hand moved in the last episode, Alex has high hopes for his recovery, while she treats a patient who already has multiple surgeries under his belt. Meanwhile, Charlie coaches a young man killed in a roofing accident who has unfinished business with his severely injured brother.

A sleep-deprived Alex takes on a night shift in the ER where an all-star hockey enforcer may be skating full-speed towards an early death. Meanwhile, Charlie meets a suburban punk who is facing the biggest fight of his life.

A high profile double hand replantation becomes Alex's (Durance) chance to prove to Kinney (Wendy Crewson) that she is still capable of being Chief Surgical Resident. In the ICU, Maggie (Ross) believes a homeless man may have been misdiagnosed.

When a severely injured man under the spell of hypnosis can't remember his identity, the hypnotist who put him under is called into the hospital - where he uses his psychic ability to connect Charlie and Alex.

A routine surgical procedure goes awry when Alex's patient, a soon-to-be-wed young woman, falls into a coma. While Alex struggles with a case that hits close to home, Joel treats a patient who does his own body modifications, and Charlie finds himself drawn to Alex's coma patient in the spirit world.

With Charlie's life hanging in the balance, Alex and Dawn go head-to-head over who gets to be his legal decision maker - but are forced to put personal matters aside when they scrub into a heart transplant surgery together. Charlie, meanwhile, is in no mood to talk to the heart donor - a deceased prisoner.

Charlie’s ex-wife, Dawn, has pulled the plug on his ventilator. All that’s left now is to wait for his breathing to stop. Devastated, Alex vows to stay by Charlie’s side. Meanwhile, Charlie – resisting his death – bumps into Mack MacIlreath, a recently deceased colleague, who has come to help Charlie die. Alex decides to lawyer up and appeal to the Consent & Capacity Board. While the process gets started, Alex is pulled away to meet with a patient: a young woman named Bea, who Alex performed surgery on while working as a first year surgical resident under Dr. Charles Harris. Bea’s check-up is all clear, but Mack and Charlie fear that she was misdiagnosed. And if Alex doesn’t catch it before Bea walks out of the hospital, she could die. Elsewhere, Joel’s hand is broken and he cannot operate until it is fully healed. Stuck with doing consults, he takes the case of a choir singer who makes a “miraculous” recovery from her paralysis.

When Joel gets cold feet in the OR, Kinney takes him with her on a Continuing Medical Education assignment in her hometown to help clear his head. During their field trip, a woman gets pinned underneath a truck and Joel and Kinney lead the rescue effort. Meanwhile, Charlie meets a newly deceased therapist who suspects it’s an emotional block that is keeping him in his coma. Encouraged by Charlie breathing on his own, Alex continues her rounds and diagnoses a fitness buff with a rare condition.

A passenger's illness forces a plane to land; when Alex performs emergency surgery on the patient, she realizes a deadly and contagious virus may have been brought into the hospital.

A last-resort operation is performed on Charlie, who must confront his past in order to awake from his coma. Elsewhere, Joel leads risky surgery on a female jockey, and Gavin crosses a line when working with an Alzheimer's patient.

In the Season 1 finale, Alex confronts game-changing questions following a monumental turn of events. Elsewhere, Joel scrambles to save a patient suffering from a rapidly spreading flesh-eating disease.

On her first day back from maternity leave, Dr. Alex Reid has her hands full when a new mother comes in following a car accident.

Dr. Alex Reid puts her reputation on the line when she questions a senior surgeon’s methods.

Alex struggles with being a mom, a surgeon and now mentoring a junior resident.

The man responsible for Alex's brother's drug problem is admitted to the hospital.

A young motocross rider is diagnosed with Leukemia, forcing Dr. Alex Reid to navigate family secrets in order to put her young patient on the road to recovery.

Alex must decide whether or not to use the info Charlie got from a patient's spirit.

Alex tries to convince Shahir to use an aggressive treatment on a brain tumor patient.

When a trapeze artists dies, a line of patients in need of his organs cause complications.

Casualties of a bomb at a local charity run arrive at Hope Zion Hospital.

Alex discovers that she unknowingly helped the bomber at the expense of a friend.

During an ice storm on Christmas Eve, Alex and Dawn fight to keep a woman alive long enough for her family to say goodbye.

Faced with a chef who refuses treatment, Alex is forced to confront how she feels about Dana's methods.

Kristine shows up at the hospital with baby Luke's blanket.

Alex and Jeremy try to solve a child's mystery illness; Charlie treats an actor; Maggie reaps the rewards of compassionate medicine.

Charlie decides to go a day without using his special abilities; Alex organizes a trip to Dana's cabin; Zach takes control of a life and death situation involving Dawn's college roommate.

Alex and Cassie try to free a young woman from her abusive partner; a patient's pacemaker malfunctions.

Kristine suffers a stroke, which impacts her memory; Alex and Charlie team up to bring her peace.

Alex and Shahir struggle to save Charlie's life.

While searching for Charlie, Alex finds a caterer who was caught in the crossfire. Grace's mother asks for a priest. Dana consults with Cassie about a male stripper.

Alex and Charlie are confused about their relationship. Alex and Maggie disagree about a car crash survivor. Dana is forced to treat an injured motorcyclist. Zach bothers Maggie about dating.

Alex makes a promise to a young girl on her birthday. Maggie organizes a surprise party for Alex. Cassie is forced to confront her fear of infectious diseases.

Charlie tries to save the arm of a man thrown from a horse. Alex joins Manny off-site to help a runaway. A rival from Dev's past arrives at Hope Zion.

Alex tracks down the father of a patient who needs a liver transplant. The new CEO of Hope Zion is at odds with Dawn. Zach faces trials in the E.R.

Alex and Maggie ask Charlie for his opinion on a patient's treatment. Zach is persuaded by a patient while transitioning the ER to an urgent care facility.

Alex and Maggie deal with a tough lawyer after surgical complications with their cancer study patient. With the E.R. now an urgent care facility, Zach and his team aren't equipped to handle an accident victim.

Charlie and Manny treat a couple. Maggie evaluates the interns. Billy asks Maggie to be his mentor. Dawn tries to get her Chief of Surgery position back.

The doctors rally together to try to save an unknown man who was struck by a subway train. Randal delivers a warning about Charlie's gift. Dr. Sydney Katz returns to town.

Alex tries to distract herself from her grief. Charlie and Shahir try to track down Alex's brother. Alex treats a young girl with kidney failure. Maggie and Sydney treat a young woman with an STI.

While Charlie tries to save a young man's life, he is haunted by a mischievous spirit.

Alex and Maggie work together to deliver a baby. Charlie treats a magician.

Alex tries to help patient who hurt himself breaking into a house. A friend of Dr. Dev Sekara has been beaten by the police; a heart patient wishes to open an animal sanctuary.

Alex is challenged about the value of holistic medicine. Charlie's abilities are questioned. Two filmmakers go to Hope Zion Hospital.

The board questions the hospital staff about Charlie's behaviour. A patient convinces Alex to use new-age techniques. Shahir agrees to do an in-utero surgery.

Alex has to put her concerns for Charlie aside when a chance to perform a cancer surgery arises.

Alex and Charlie put their wedding plans aside. Zach takes a special interest in a case. A coma patient who wakes up with no memory.

Alex and Charlie rush to the scene of a mass casualty accident involving a bus full of teenagers.