Lex Luthor discovers Superman's vulnerability to Kryptonite, and attempts to exploit this weakness to rid himself once and for all of the Man of Steel.

After toxic chemicals transform janitor Rudy Jones into the energy-draining Parasite, he imprisons Superman, intent on keeping the Man of Steel as his own personal power source.

Brainiac, once Krypton's all-knowing planetary computer, comes to Earth as part of his information-gathering trek across the galaxy. But, as Superman discovers, Brainiac's intent after gathering the world's knowledge is to destroy the Earth.

Intergalactic bounty hunter Lobo is employed to capture the Man of Steel, but thanks to a double-cross by the rare-species-collecting Preserver, both Superman and Lobo end up trapped in the Preserver's personal zoo.

When embittered scientist Earl Garver goes into a coma before revealing the location of a ticking bomb, Superman risks enlisting the Parasite to drain the information from Garver's mind.

Superman decides to release Mala, a Kryptonian criminal, from the Phantom Zone, but when Mala proves too power-hungry for this world, Superman tries to send her back. Mala escapes with the Phantom Zone Projector and releases Krypton's most notorious traitor, Jax-Ur.

Superman and Professor Hamilton start building a new Phantom Zone projector to balance the odds. However Jax-Ur and Mala manage to send Superman into the Phantom Zone, and then destroy the Projector. As their decimating attacks begin, it's up to Lois and Professor Hamilton to rescue the Man of Steel in time.

A giant humanoid creature with incredible strength and heat-sapping abilities, falls to Earth and now threatens the planet. Superman has to fight the creature's advances and send it back into outer space.

Edward Lytener escapes from Stryker's Island and becomes Luminus. He hopes to render Superman powerless by hijacking a number of satellites so that they permit only red light to filter through from the sun.

Lois stumbles into a parallel world where Superman and Lex Luthor work together as dictators of Metropolis.

A monkey returned to earth from space begins to grow incredibly large and threatens Metropolis.

Superman teams up with Orion, an escapee from Apokolips, to take on Darkseid as he prepares to attack Earth.

Darkseid invades Earth with the help of Steppenwolf. With help from the citizens of Metropolis and the arrival of troops from New Genesis, Superman is able to stop his advance, but not without losses.

Superman breaks free of Darkseid's control and goes to Apokolips to try to stop Darkseid once and for all.