Ippo joins Takamura, Kimura, and Aoki in a training camp near the beach.

The boxing stadium tremble with excitement, the crowd goes wild and wants to see only one thing, the victory of Jimmy Sisfer, and the defeat of Ichiro Miyata ... While the gong is about sound, Payao and baby Chana brother are on their way to see one of the most beautiful game of the life Miyata. Back at the stadium Runpini, Miyata can only see the reputation of Jimmy Sisfer, while his father described the situation of the failed against Ichiro. Payao Chana and finally arrives at the stadium before the match is over.

Makunouchi Ippo is the new Featherweight champion of Japan and is now ready for his first title defense. His opponent, the former Jr. Featherweight champion and a medical student, Sanada Kazuki. In addition to this feud, Sanada is being coached by Kamogawa's former rival, Hama Dankichi. What makes things worse is that Sanada works at the same hospital where Kumi is a nurse at and everybody at the hospital wants Sanada to win. Not only does Ippo have to defend his title, he has to reclaim his love.