As a lethal powers-enhancing drug is unleashed on the public, Detectives Walker and Pilgrim seek out the criminal mastermind behind it with the help of iconic Power, Retro Girl. As clues come to light, Walker considers the possibility that Wolfe, his dangerous former mentor turned nemesis, might have the answers he seeks.

Johnny realizes that's his new drug is dangerous, but is it too late to stop Wolf before all hell breaks loose?

As Retro Girl, Zora and the heroes of the world rush to stop the escape of Wolfe from The Shaft, Walker realizes he must face him alone, the inevitable clash between mentor and disciple that will unravel the deep-seated history between them.

After Wolfe pleads to end his life, Walker and Pilgrim must act quickly to stop Johnny Royalle from meeting with Wolfe in The Shaft. Meanwhile Zora struggles with her newfound fame, while Calista becomes more desperate to discover if she truly is a Power.

In order to persuade him to join his new cause to annihilate Wolfe, Royalle reveals to Walker the true nature of Sway and the inevitable devastation it will cause if Wolfe ever escapes. Meanwhile, as the message of Chaotic Chick spreads rapidly with fatal results, it finds its biggest platform yet in a publicity stunt orchestrated for Retro Girl's charitable foundation.

Wolfe has escaped prison, it is now up to Christian and Co to stop his reign of terror from sucking the life of all the power teens that took Sway.

The world is turned upside down by the seemingly impossible and horrifying murder of retro girl. Pressure is on the powers division to bring the perpetrator to Justice, but when Walker is pulled off the case for being too close to the victim, and may be a suspect himself, he must go off-the-books to avenge the woman he loved.

On the day of Retro Girl's funeral, Detectives Walker and Pilgrim prepare to combat violence between rival gangs The Quantums and The Hacks. Hoping to fill her place, Calista makes her public debut as New Retro Girl. Still reeling from Retro Girl's death, and with her murder officially closed, Walker doggedly pursues a suspect he believes to be the real murderer.

Commander Cross unofficially reopens the Retro girl case, ordering Pilgrim and Walker to lead a covert investigation that may put them in a life-threatening situation. Meanwhile, Los Angeles goes in lockdown mode as gang warfare reaches a fever pitch, pulling the revered Power, SuperShock out of retirement.

New evidence suggests the main suspect and Retro Girl's murder may be a rare power gone rogue. With contempt between the Powers Division and the FBI escalating to a breaking point, Walker attempts to gain Agent Lange's trust.

As Calista is about to be crowned the newest shining star of the Powers universe by Conrad Moody III, CEO of the most powerful Powers merchandising company on the planet, a valuable member of the community is murdered. With Walker and Pilgrim suspended, they are powerless to stop the city from unraveling around them.

Powers start dropping from the sky and Walker suspects an old friend is behind it. Pilgrim pursues Ghost believing he is responsible. Calista confronts SuperShock but the encounter causes her to reconsider being a power.