Laura Dal Fiore is a separated mother of two children, Emanuele and Nina. Their life flows peacefully until Paolo Giorgi, a widower, moves onto her landing with his teenage daughter Cristina. The two families, with opposite habits and tastes, end up hating each other.

Paolo has lost Laura's phone number and is desperately looking for a way to find it, while she disconsolately awaits a call from him. Fortunately, the colleagues of "Tu donna" intervene to resolve the situation. But will the magic of their first meeting make the two digest the discovery that they are each other's hated neighbors?

After discovering that Paolo and Laura were neighbors, advised against by their best friends, they decided not to continue their acquaintance. The situation is aggravated by the continuous clashes at school between Emanuele and Cristina, which even end up in front of the principal. Attempts at apologies and reconciliation seem to fail miserably and Laura ends up accepting an invitation to dinner from Sergio, Nina's teacher.

Paolo and Laura have been secretly seeing each other for ten days, but they still haven't been able to make love. Both would like to, but, confused by Monica and Michele's well-meaning advice, they are afraid to take the initiative, and when they finally decide, they can't find the right place.

Paolo and Laura are now a steady couple even if they continue to hide from their children, thus accumulating excuses and lies. However Cristina, by chance, sees her father kissing her neighbor and is shocked, so much so that she tells Emanuele, who begins to investigate.

To improve the situation on the landing, Laura decides to organize a dinner with Paolo's family, but things don't go exactly as hoped: Emanuele extends the invitation to the grandparents, the sweet Mario and the cruel Clelia and Cristina calls the elderly aunts Filomena and Sofia. Laura herself also thinks about expanding the number of guests, inviting Monica and her sister Stefania, a woman sui generis, and Paolo who brings his friend Michele. With all this confusion the dinner turns out to be an absolute fiasco.

Laura and Paolo finally manage to sleep together for the first time, but Emanuele and Cristina do everything to make the situation complicated. The woman, seized by an attack of acute jealousy, begins to see the ghost of her neighbor's wife.

It's time for Paolo too to come to terms with a ghost from the past: Laura's ex-husband, Riccardo Balestrieri, a successful writer, is returning to Rome for Christmas and will be a guest at the Del Fiore home. Laura's reassurances are useless, her new man doesn't seem to like this thing.

Christmas is approaching, and Paolo suggests that Laura spend it together, but Riccardo's arrival has upset all of the woman's plans, also because on December 25, Riccardo plans to give Emanuele a little speech. Paolo, fed up with Laura's ex-husband and disappointed by her behavior, is offended.

Emanuele cannot accept his father's revelation and refuses to speak to his parents. Even Paolo, after an initial moment of euphoria, begins to wonder why Laura has hidden this truth from him for so long.

Emanuele is increasingly in crisis and is starting to have problems at school too. Clelia suggests a psychologist, but Paolo advises Laura to be patient. After a day in the countryside with grandfather Mario, things seem to have settled down, but the next day Emanuele secretly waits for Peter, Riccardo's partner, hits him on the head with his helmet and runs away.

Peter is rushed to hospital while Emanuele disappears without leaving any trace. Paolo also disappears, for just one night, and thanks to Natascia who, feigning a breakdown in the car, blocks him in a country house for the umpteenth, useless attempt at seduction.

Laura still can't believe it: she's expecting a baby. Locked in the newsroom bathroom for yet another pregnancy test, Monica becomes suspicious that it doesn't take long for her to understand that the result is positive. It's amazing news, but it sends her into a crisis.

Paolo and Laura have decided to move in together, but they don't know how to tell their children. And they don't even know how they could take the news of the pregnancy. Between Laura's nightmares and Paolo's impediments, neither of them is able to speak to either Cristina or Emanuele, but time is running out and the baby bump grows.

Paolo, Laura and the boys begin to savor the joys and problems of the new coexistence as a single extended family. Meanwhile, Giulio and Stefania organize their surprise wedding and Paolo's aunts, after discovering that their cooking is bad, decide to take a course to learn how to cook.

Cristina can't believe that Davide Palmieri, the most handsome boy in school, has fallen in love with her, and tries to keep her story hidden from Paolo, whose overprotective father's reaction she fears. When Paolo discovers the two at home, however, he responds in a completely unexpected way.

Employment is now in the hands of Emanuele, who is becoming a point of reference for the whole school: a unique opportunity to affirm his identity among his classmates after years of anonymity. On the other hand, the occupation is offering Cristina another opportunity, that of sleeping one night with Davide. And to make love to him for the first time.

To have more time to spend with her Davide, Cristina asks Emanuele to extend school work by one day. Monica is delighted with her story with Ermanno and she would like to organize a threesome with Michele, to thank him for having organized the meeting. But the man has understood that he loves Monica and would like to refuse.

Laura has to deal with a terrible reality: she has lost her child while Paolo, desperate, doesn't know how to console her. Monica, suspicious, asks Ermanno to reveal the whole truth about their meeting and discovers that Michele has a hand in it.

Depressed, Laura no longer leaves the house except for walks with her little daughter and thanks to a meeting in the park she is convinced to return to the editorial office where she discovers, by chance, that her sister Stefania is expecting a child.

Laura is in crisis and Paolo doesn't seem to notice it, continuing his life as if they hadn't lost the child. When the woman breaks out in front of her partner and the gynecologist, the two start a furious argument in which Laura blames Paolo for what happened. Their story seems to have come to an end, as well as that between Cristina and Davide.

Just as in the Del Fiore-Giorgi house a damp spot expands, looming over everyone's heads, so the crisis between Paolo and Laura worsens, shattering their relationship. The only solution the two can find is to raise the demolished wall and each return to their own apartment.

Paolo and Laura go back to living in two different houses, Cristina is in Rome and Davide is in Athens, Cristina, Emanuele and Nina are no longer siblings, Michele and Monica are divided: nothing goes as it should. And Paul only makes the situation worse.

Laura hates Paolo because she is convinced that he cheated on him with Natascia and does everything possible not to meet him. Repenting for what happened, Giorgi finally realizes his feelings and is determined to ask Laura to marry him. Meanwhile, Del Fiore and Riccardo spend a night of passion unaware of Peter, the man's American companion.

While the preparations for the wedding are in full swing, Laura is very agitated: should she or shouldn't she reveal to Paolo that she has cheated on him with Riccardo? Monica and Riccardo himself advise her not to ruin the moment but, the night before the wedding, the woman confesses everything about her.

Paolo apologizes, but he just can't bring himself to marry Laura: he continues to imagine her in bed with Riccardo. So he leaves, leaving her at the altar. Laura can't believe it: she gets into a sort of hysterical fit, but then she can't help but surrender to the evidence of it.

Monica and Michele and Laura and Paolo are about to get married. The two couples, planning a romantic wedding for four, are taken by anxiety and agitation: Laura hopes that this second occasion, in the company of her best friend Monica, she will go better than her. Meanwhile, Cristina and Emanuele are going back to school.

The big day has arrived: Monica and Laura prepare for the wedding, unaware that their future husbands are still asleep. It will be a phone call from the two brides to wake them up and they, panicked, will try to arrive in time for the celebration. Even Giulio and Stefania, witnesses of the wedding, are getting ready, but an emergency upsets their plans.

Monica does not accept Michele's death, and learns that he too would have liked to have a child with her. Paolo, on the other hand, in order not to think about the loss of his best friend, gets busy, with Adriano's help, organizing the perfect funeral. In the meantime, Stefania has given birth to the twins, Rebecca and Rachele.

Lea and Ermanno spend the night together and, for Lea, the event must remain a secret. Meanwhile, Cristina enrolls in a kick-boxing class where she meets Raoul, a handsome boy, who turns out to be her teacher. Laura tries to get Paolo to react, making him read an essay by Cristina, in which her daughter spoke about Michele. Monica makes a shocking announcement.

Laura's success spreads quickly thanks to a flattering article in a newspaper, but the girls in the editorial office aren't as enthusiastic about her friend's book. In fact, Maya, Rosa and Lea recognize themselves in the portraits of women that Laura has done in her book and have no intention of forgiving her friend for having been placed in the public square.

Laura tries to clarify with her friends, but fails to get any results. The relationship between Monica and Adriano is going swimmingly: the awkward ornithologist manages to satisfy every slightest wish of the future mother, but from Paradise Michele is desperate for the choices of his loved ones.

Stefania has disappeared. Giulio thus finds himself alone, taking care of her twins while Laura and Paolo try in every way to track her down. Paolo, meanwhile, also involved in Valeria's enthusiasm, decides to throw himself into the nursery adventure, even though he would like to talk about it first with Laura who, however, is too busy with the disappearance of her sister.

Stefania, unable to stay away from the girls, secretly returns home, but is surprised by Giulio who decides to put her to the test. Meanwhile, Paolo finds himself having to deal with Laura's continuous professional successes which, on the one hand, help the family budget, on the other they expose him to some concern.

When Laura returns from her business trip, she finds no one at home to welcome her. The new writer realizes that perhaps she is neglecting her family and decides to put her career aside to devote more time to her children and to Paolo, but Clelia warns her, warning her that certain occasions only happen once in a lifetime. life of her.

Laura has to leave again to meet a French publisher and doesn't know how to tell Paolo who, in the meantime, is in big trouble with the nursery. Her partner, partly out of guilt, partly to show closeness to him, thus decides to invest part of the proceeds from the book in the quiet of a greenhouse. Michele appears to Monica in a dream and reveals that a man is about to enter her life.

Laura leaves for Sorrento without clarifying herself with Paolo, who is increasingly jealous of the relationship that the publisher has with his partner. Both, hoping for the other's phone call, wait for the situation to stop. Despite the magical moment in her career, Laura is sad and she always thinks of Paolo from whom she expected more support in such a delicate moment in her life.

Paolo dreams of Laura and Marco taken by passion, but then he finds himself in Michele's "office" who reassures him about his partner's behaviour. The woman, over the phone, is unable to confess to her companion about the evening spent with her editor. Giulio tries to win Yang's affection by giving him gifts, but it will be Clelia who restores balance between the two.

Christmas is upon us and Monica, who intends to let her child experience the spirit of the holiday, entrusts her brother-in-law with the task of preparing dinner at their home. After talking to the woman, Adriano confides in Paolo who advises him to get distracted and think about another person.

Everyone in the family is busy for New Year's Eve, but Cristina has no desire to celebrate. Laura proposes to Paolo to invite Valeria and Gianluca to the party organized by Clelia. Mario, in the grip of jealousy, asks his wife for an explanation about her association with the man unknown to him and she confesses to him that it is a past love affair.

The relationship between Paolo and Laura seems to be booming after the newfound intimacy, but Laura feels that Paolo is hiding something from her. On Michele's advice, Paolo has decided not to be sincere with his partner and, upon hearing the news that Valeria has left Gianluca, he fears that her betrayal may come out into the open.

Haunted by remorse, Paolo dreams that everyone has discovered his betrayal but when he wakes up Laura reassures him of her love, promising him that she will never leave him. Monica discovers that Adriano spent the night at Bea's and is furious with jealousy while Mario clearly tells Clelia that he will never follow her steps again.

Laura thinks back to Paolo's confession and can't find peace for her partner's betrayal. Paolo tries to fix it, but the writer doesn't listen to reason and forces him to keep the secret with her children. Adriano continues to frequent Bea's house and Monica, to create havoc in his brother-in-law's life, implements a plan to sabotage his habits.

Monica, after spying on Adriano, is obsessed with his physical prowess. The ornithologist gives her walkie-talkies because she has decided to accept Bea's proposal to move in together. In the editorial office, Monica reproaches her friends for not encouraging her to indulge Adriano's feelings because she has now lost him definitively.

Laura wants to put boundaries between her and Paolo and labels everything in the house to underline their separation. Even her friends encourage the tension strategy that the writer is carrying out, while Paolo gets angry. Adriano experiences a real metamorphosis after Monica's declaration of love, showing off her physical qualities.

Cristina flies into a rage when Paolo asks her to end her relationship with Raoul. Laura is worried and tries to understand with her friends what the nature of her partner's illness is and, for this reason, she goes to find Valeria. The nurseryman admits that she has feelings for Paolo, but that she has never seen him again.

Monica suffers from nightmares after discovering that Adriano has a wife. Meanwhile, from Paradise, Michele ascertains the veracity of his brother's secret marriage. Aware of Raoul's illness, Laura overcomes her embarrassment and offers her support to Cristina.

Monica believes that Adriano doesn't really love her, but sees in her a human case to save while, from Paradise, Michele is moved when he hears his brother confide in Paolo the decision to recognize his son. Emanuele has lost his mind, he can't find peace over Viola's abandonment and this leads him to even neglect his studies.

Paolo leaves home and moves into a new apartment while waiting for things to settle down. However, the separation does not help the couple and both think of the moments spent together. Emanuele is in a deep crisis. Viola makes sure of her condition and he confesses to her that she will never find a boy who loves her the way he loved her.

The day of graduation arrives. Cristina and Martina use all the existing copying techniques while Emanuele is tormented by thoughts. Viola had decided to reveal her love to her boyfriend but Cristina dissuades her so as not to disturb the exams. Meanwhile, the tracks are not those expected by the aunts and the whole class panics.

After having excluded Viola from his thoughts, Emanuele threw himself headlong into the study and prepared a 1,400-page essay with the aim of astonishing Ugolino. Meanwhile, Paolo feels he has failed and tells Cristina that they will soon find a new house to move to.

Paolo doesn't have the courage to tell Laura that he doesn't want her to leave. Even Laura is waiting for nothing but these words, but neither of them manages to tell the other. Emanuele and Cristina, still grappling with the Maturity, have to deal with an unknown and very bad professor.