The BAU hits the road to track down a pair of young lovers on an interstate murder spree. Also, Prentiss hears frightening news from her former boss at Interpol.

The BAU is called to a North Carolina resort town after a woman is found badly injured and another woman is missing. On arrival, the team discovers these two women are not the only victims.

The BAU tries their luck in Atlantic City when the team is called in to investigate a series of ritualistic casino-related murders. Also, after a spat with her boyfriend, Kevin, Garcia thinks she and Morgan may have gotten a little too friendly with each other.

A serial killer is executed, in Oklahoma, a copycat shows up and the BAU are called to find him. Meanwhile, Prentiss gets nervous about a real estate purchase.

The BAU travels to Santa Monica when burned bodies of homeless people begin showing up by the famous pier. Also, Rossi reconnects with his former Marine sergeant from Vietnam.

The BAU travels to Los Angeles looking for an UnSub who is kidnapping nannies and the children they care for on the same day each year.

As Hotch fights for his life due to complications from his stabbing at the hands of George Foyet, a.k.a. "The Reaper," he experiences visions of his late wife, Haley, and his nemesis, Foyet. Meanwhile, the BAU searches for a missing teenager and investigate her estranged father as a suspect in her disappearance.

When three bodies are found with animal and human bite marks in a shallow grave near Milwaukee, the BAU has puzzling questions to answer. Meanwhile, Reid and Garcia work out for a company fitness test, but try to hide their preparation from Morgan.

Rossi will go to any lengths to prove that Elias Voit is Sicarius. But Voit turns Rossi into his own worst enemy, putting his future at the BAU in jeopardy.