Fitz travels to Guatemala to rescue a man who has bleeding in the brain. However, because the bleeding is so severe, the man will not make it back to Toronto due to the cabin pressure. Meanwhile, Ming has to perform a emergency delivery when her patient's baby has its neck trapped in the umbilical cord. And Chen finally realizes that there is more to life than medicine.

After Fitz takes a sick patient from China to Toronto who dies later, he is diagnosed with a mysterious respiratory illness. He is immediately put into isolation, but has infected Chen who examined him. Ming is in quarantine at home where she starts to rethink again about adoption. Bearing the scars of never knowing her father, she doesn't know if she wants to make a child go through that situation again.