Nonnatus House welcomes two new nuns. Valerie deals with a shocking case that arrives unexpectedly, and the other midwives must handle a complicated multiple birth.

Mother Mildred returns and helps a docker family tackle end-stage pneumoconiosis. Lucille cares for an unmarried teenage mother who wants to keep her baby.

Mother Mildred decides it’s time for Sister Frances to attend her first solo birth. Trixie consoles a patient who discovers she has gonorrhea.

Mother Mildred and the Nonnatus House team head to the Outer Hebrides in response to a nursing shortage.

Dr Turner and Nurse Crane must deal with an alarming outbreak of diphtheria. Fred finds an abandoned baby in a dustbin, and the team must help locate its mother.

Christmas promises to be a memorable one at Nonnatus House as Lucille and Cyril prepare for their upcoming winter wedding. The Nonnatus team are faced with their busiest Christmas Day ever as the Maternity Home is filled with expectant mums-to-be, each with their own challenging case. Luckily Mother Mildred is on hand to support the team.