The team reunite but all is not well when a change of management shakes up Nonnatus House.

An explosion at the docks brings heartache to the people of Poplar, whilst Sister Ursula continues to ruffle feathers with her unpopular decisions.

The winds of change are blowing through Poplar, as a new government paper calls for the eradication of small hospitals in favour of large general hospitals. Dr Turner and Shelagh are informed that an inspection of the maternity home will decide its fate.

An expectant mother with financial struggles enters into a painful arrangement with her cousin. As Tom provides pastoral care, he reveals why this case touched him more than most.

Nonnatus House welcomes a new recruit, Nurse Valerie Dyer. A vulnerable young man captures Fred and Violet's hearts, whilst the whereabouts of Sister Mary Cynthia is a concern.

Valerie Dyer cares for a pregnant Somali woman and is shocked by aspects of this unfamiliar culture. The nuns and midwives try to provide the best care for Sister Mary Cynthia.

Dr Turner helps the Mullucks cope with the stresses of caring for a disabled child as the terrible legacy of thalidomide becomes apparent and Nurse Crane faces an unexpected crisis.

An unexpected turn of events leads to a wedding being hastily arranged. Shelagh finally goes into labour. The arrival of the pill leads to unforeseen consequences.

The winter continues, and the team at Nonnatus House welcome their newest midwife, Lucille Anderson. Nurse Crane and Dr Turner care for an elderly cancer patient facing eviction.

Lucille faces racism and prejudice when a new mother falls ill. Sister Winifred is keen to have fathers be more involved in the care of their babies.

A pregnant mother hears a devastating diagnosis. Fred and Violet organise a beauty contest. Trixie and Christopher's relationship feels the strain.

Sister Julienne is drawn into the heart of a different culture when she is called upon to help a Pakistani family. Having come to terms with her own childlessness, Mumtaz Gani is heartbroken when her husband Saddiq brings home a second wife who is eight months pregnant. Sister Julienne must help Mumtaz come to terms with this new addition to her family.

Lucille must win the trust of a mother who is terrified of giving birth. Nurse Crane and Dr Turner are anxious to find a possible smallpox sufferer.

Barbara gets involved with a recently widowed pregnant woman, and Sister Monica Joan has her cataract surgery.

Dr Turner gets involved with a troubled young man, and Lucille makes new friends. Meanwhile, Barbara lies ill in hospital.

The team must rally to prepare for Sister Monica Joan's birthday. Meanwhile, the closing of a nearby maternity home brings an influx of expectant mothers to the Nonnatus midwives.

Nonnatus House welcomes two new nuns. Valerie deals with a shocking case that arrives unexpectedly, and the other midwives must handle a complicated multiple birth.

Lucille helps elderly hoarder Clarice Millgrove who is struggling to keep her independence; Sister Hilda and the team work hard to help a Ghanaian family with an undiagnosed illness; Violet puts herself forward in the upcoming elections.

Valerie helps a struggling mother accept her son's birth defect. The Turners oversee a measles vaccination trial at the clinic as the team prepare for the Whitsun bank holiday.

The team tries to unite an estranged mother and daughter who are both pregnant. Trixie's friend is devastated to discover she is pregnant.

Poplar welcomes a brand new cervical cancer-screening clinic to the Institute and Dr Turner, Shelagh and Trixie are pleased to be part of the exciting new venture.

Mother Mildred returns and helps a docker family tackle end-stage pneumoconiosis. Lucille cares for an unmarried teenage mother who wants to keep her baby.

Mother Mildred decides it’s time for Sister Frances to attend her first solo birth. Trixie consoles a patient who discovers she has gonorrhea.

Sister Hilda digs deep to give her terminally-ill patient her final wish whilst the Turners must prepare to say goodbye to May. Fred and Reggie are keeping secrets from each other.

Dr Turner and Nurse Crane must deal with an alarming outbreak of diphtheria. Fred finds an abandoned baby in a dustbin, and the team must help locate its mother.

Sister Julienne cares for a pregnant prostitute, while Dr Turner puzzles over a mysterious string of symptoms.

Lucille is seconded to St Cuthbert's when a ward sister is off sick, but a lift malfunction sees her spend the evening with mother-to- be Connie instead of her planned rendezvous with Cyril.

Sister Julienne volunteers to put up four trainee doctors at Nonnatus House while they undertake the practical aspect of their obstetrics diploma, hoping the exercise will remind the council how vital the home is to the community and help remove the threat of demolition.

Sister Frances is at a loss when she cares for diabetic and recovering cancer patient Albert Calthorpe whose fiercely independent wife Grace refuses to accept further help, despite caring for her husband, her elderly mother and her pregnant daughter.

At the Turners, Shelagh receives a phone call from the Hong Kong adoption agency, which has the alarming news that someone from May's past has arrived in the UK and wants to see the little girl.

Trixie helps a blind mother, Marion, care for her new baby, but trouble starts when Marion’s sister calls Social Services to intervene.

Sister Julienne decides it is time to take matters in hand when a letter arrives from the council saying that it will cut funding to Nonnatus House and no longer pay for the accommodation, and goes to see Violet at one of her open sessions as a local councillor.