In the pilot of Smash we are introduced to Tom Levitt and Julia Houstona song-writing duo who had planned on taking a break from the business of Broadway but, find themselves drawn back in when they get the desire to produce a musical based around the life of Marilyn Monroe. When a demo of one of the tracks goes viral the project attracts the eye and ear of tenacious producer Eileen Rand and, although causing a conflict that of director Derek Wills. But the biggest and most important task is to find their Marilyn after, auditioning a range of girls they whittle it down to two but, who do they go for. Ivy Lynn a veteran of the stage who wants to break away from the chorus line to get her break as a lead or Karen Cartwright a fresh talent who is trying to follow her dream of becoming a star.

Karen must learn to advance in the high-stakes world of Broadway, as Derek hosts a party for hot young star Lyle. Eileen tries a sly new strategy for raising funds, while Tom goes on a first date.