The Pan Am crew rolls the dice in more ways than one in glamorous Monte Carlo: Kate and Maggie square off for the attentions of a handsome passenger, but things get more complicated when Kate learns the sexy stranger is involved in her next covert mission; and Dean gambles with his career when an attractive, wealthy woman on the flight tempts him -- and he later discovers who her flying companion is.

Maggie is perilously close to losing her job for insubordination, but still manages to maneuver her way onto the flight down to Rio de Janeiro. She reflects back on the rocky path she took to land her dream job, but it's her decision to do whatever it takes to keep it that surprises even her. Meanwhile, Kate has earned her stripes as a courier, but when she is given a difficult mission involving Niko, a Yugoslavian diplomat, she's unsure how to manage the task, as she tries to juggle their deepening personal relationship with her assignment. Finally, Ginny and Dean continue to play with fire in Rio, but Ginny's game playing with both Dean and her boss and lover, a Pan Am executive, is a source of contention with Dean.

Sparks fly between Laura and a sailor on a special – and unusually wild -- Pan Am flight bringing servicemen home, leading Laura to realize what she’s really looking for in a man, as well as opening her eyes to the malicious racial climate in the country. Meanwhile Kate’s complicated mission to turn Niko to work for the U.S. government culminates in dramatic fashion, threatening their personal relationship.

Dean is surprised by the ramifications of his fling with Ginny when she stalks him to Rome with, frightening consequences; Colette takes a precocious unescorted minor, Charlie, under her wing, who promptly develops a major case of puppy love; Kate struggles with the dangerous fallout of her strong connection with Niko; and Laura is spellbound by a handsome photographer, Graham, who shot her for the Life cover.