While being pursued by the Enforcers, Spider-Man has to protect Norman Osborn from the vengeful supervillain Vulture.

When. Dr. Curt Connors' attempt to regenerate a new arm accidentally transforms him into the Lizard, Peter, Martha, Eddie and Gwen search for a cure.

As Peter Parker and Harry Osborn try out for the football team, Spider-Man must face convict Flint Marko, newly transformed into the Sandman in order to destroy Spider-Man.

Venom -- the merged entity consisting of Eddie Brock and the symbiote -- attacks Spider-Man through the people he loves most.

Both Liz Allan and Gwen like Peter. Whom should he pursue? Meanwhile, Kraven the Hunter has come to New York City to make Spider-Man his prey.

Amazingly, Peter is invited to Flash Thompson's birthday bash. Meanwhile, Spider-Man has to party with Sandman, who's looking to make his big score.