Following a rash of fatal drug overdoses, Da Vinci learns that one of the dead addicts had an infant, who is missing. Manny, a police informer leads Leary, with new partner Angela Kosmo, to the woman's drug dealers. They arrest Todd and Sioux, and through them Larry discovers that the killer heroin came from a French-Canadian supplier who, along with his partner, was murdered, gang-execution style, just days previously.

When a young woman's dead body is dumped in an underground parking lot with no apparent signs of injury, Da Vinci and the police are intrigued. Patricia's autopsy turns up surprising answers and Da Vinci's investigation draws him into the world of S&M. Someone with a lot of power is trying to manipulate Chief Coroner James Flynn and Da Vinci into keeping the facts and the faces of those involved with Mistress Harriet hidden.