Kate has started a new Nurse Practitioner course and is full of fresh ideas for the ward. So when a suspected case of anthrax walks through the door she takes charge and puts her staff in quarantine.

Beth is still convinced nurse Justyn tricked her about his sexuality just to get her into bed. So in true Beth fashion she plans revenge and plays a trick of her own.

Anji turns up to work an hour and a half late after a champagne breakfast, a patient susses that she has been drinking and Kate has no choice but to take disciplinary action against her friend. Then, to the surprise and horror of her three friends, Anji quits her job.

After quitting her job at the hospital, Anji has taken the plunge and decided to go travelling around India. Beth is anxious about what life will be like without her: she secretly worries that Anji is the only reason that Lia and Kate are friends with her. And then she catches the two of them having an impromptu drink in the pub without her...

Back on the ward, Dr Callum is jealous of nurse Justyn's popularity with the patients. When he discovers this is down to Justyn's 'professional campness', he persuades Justyn to teach him the basics.

With her 30th birthday fast approaching, Kate worries that her age is starting to show in the most unusual of places. She is happy about her budding relationship with new registrar Dr Peter Compton, despite the ridicule she gets from Beth and Lia when they realise she and Peter haven't had sex yet.

The nurses at St Margaret's are feeling increasingly under threat from violent patents. Unimpressed with the new, prepubescent security guards, Peter uses his army training to give self-defence lessons to the rest of the staff.

Kate's mother, Valerie, surprises Kate with a special birthday visit. Unfortunately, Valerie is more interested in joining Lia and Beth on a boozy night out than spending quality time with her daughter. But Lia and Beth have a surprise - or two - in store for Kate.

As her wedding to Peter approaches, Kate takes him to visit what could be their dream home in the country, but he doesn't seem overly impressed.

Anji proudly shows off her new baby, but still hasn't made up with Callum, who is avoiding her in the hospital.

Beth and Rob are getting on brilliantly and already seem like they've been a couple for ages.

Meanwhile, unhappy Lia sees everyone else around her moving on. Emma can tell her mum hasn't been happy since Jamie left and tries to convince her that a trip to Australia may be just the tonic