After the events in Canada, Bette is on the run from authorities with her daughter. Shane reverts back to her old habits but gets a surprise from her father's wife. Meanwhile, Helena tries to get used to living without her mother's money, Max attends a support group, and Kit has trouble with her pregnancy.

Alice meets Papi, a girl who lights up on The Chart even more than Shane. Jenny is interviewed by a gay writer. Bette's new boss has some surprising news for her. After Helena's departure, a new guy takes the reins at the studio as Tina's new boss. Meanwhile, Max goes out on a date with a straight girl.

Tina throws a cocktail party to get her gay and straight friends to know each other better. Penniless Helena is looking for a job. Shane takes care of her little brother, Angus' band is on the verge of a breakthrough, and at the art college, Bette's teaching assistant is having feelings for her. Meanwhile, Phyllis attends a ladies-only Texan night at The Planet.

Bette meets the new resident artist, Jodi, but a controversial arts project in her class upsets a potential donor for the college. Papi challenges Alice and the girls to a basketball game. Max reveals a secret to his girlfriend. Jenny schemes her way into meeting Stacey Merkin's girlfriend. Meanwhile, Shane is struggling to scrape up money for a hospital bill.

Bette's forbidden relationship with her TA, Nadia, could jeopardize her career. Alice, on the other hand, ends her affair with a married woman after meeting her husband. She also gets upset by one of Jenny's short stories which gets published in a magazine. Meanwhile, Angus is caught in a compromising position.

The girls attend a movie premiere sponsored by Shane's underwear campaign. Papi teaches Helena and Alice how to play poker for a high-stakes private game hosted by a high-profile female gambler. Bette disagrees with Tina about Angelica's education, and goes on a date with Jodi. Meanwhile, Phyllis is having trouble letting go of Alice.

Tina's boss orders her to get the movie rights for Jenny's Lez Girls. Helena considers whether she should take up on Catherine's offer to pay off her gambling debt. Paige and Shane volunteer at Shay's school to teach the kids about tolerance. Meanwhile, Alice and Tasha take it slow, and Bette learns something about Jodi's past that puts kinks in their relationship.

Tina gets introduced to Jodi, and has second thoughts about leaving the lesbian life behind. Alice and Tasha argue heatedly over politics. Max hires an intern to help him with the workload on OurChart. While Shane and Paige steam up the car windows, and Catherine and Helena make a winning team at the poker tables, the rest of the girls attend the unveiling of Kit's new single at The Planet.

Jenny and Tina look for the right movie director but butt heads over creative differences. Phyllis' husband drops by unannounced at Alice's place. Bette is falling hard for Jodi and lets her emotions interfere with her work. Kit manages to crack through Papi's hard outer shell – with unexpected consequences.

The girls spend a day at the horse tracks where Catherine and Helena risk it all. Max takes Grace home to meet his estranged family. Bette hosts a dinner party but her obsession over every detail gets on Jodi's nerves. Meanwhile, Jenny and Tina agree on a director, Kate Arden, who quickly becomes interested in Tina.

Bette finds out that Jodi's been offered a job at an art center on the East Coast. Tasha's memories of the war continue to haunt her, and she is ordered to keep her sexual orientation a secret. Meanwhile, Shane plans a surprise for Paige, Helena is kicked out of the hotel, and Max comes to a decision regarding his job.

Bette seeks Tina's advice on how to get Jodi back, but is surprised to learn that Tina no longer wants to be straight. Alice is devastated when Tasha is called in for another tour in Iraq. Meanwhile, Phyllis seeks divorce, Jenny is excluded in any decisions regarding the movie, and Helena frees herself from her entanglement with Catherine.

Shane tries to deal with her betrayal to Jenny as they both attempt to figure out their feelings for one another. Shane awkwardly tries to apologize to Jenny, who responds by threatening to evict Shane from her house. Meanwhile, Bette and Tina get worried when Angelica comes down with a fever which gradually gets worse. Alice and Tasha cannot decide whether to break up or stay together since their different views on life strain their romance to the breaking point. Elsewhere, Helena and Kit celebrate after taking over SheBar nightclub and formally rename the place, 'HIT!'

Bette and Tina talk about expanding their family and beginning a new life but the plan could be ruined when Bette bumps into an old friend with dangerous potential; Alice and Tasha ponder their compatibility as they seek counseling; an old flame appears, sending Helena reeling; and Max is faced with an extraordinary situation.

The negative of “Lez Girls” goes missing; Shane’s incessant apologizing to Jenny finally gets noticed; Alice’s feelings are hurt when Jenny denounces her desire to write a screenplay; Phyllis lets Bette in on a suppressed secret; and it’s opening night at Kit and Helena’s new club, HIT!

Shane and Jenny are still melting over each other; Bette and Tina go to Nevada to meet a potential birth mother; Max is trying to deal with being pregnant; Alice and Tasha play matchmaker; and Kelly Wentworth may have what Bette needs.

Jenny writes another script that sells; Bette and Kelly go into business; Alice and Tasha have a third-wheel crush; the girls plot a sting operation to test Dylan; and, Jenny encroaches more on Shane.

Jenny throws a baby shower for Max; Bette and Tina hit a roadblock in the adoption process; Bette goes solo to her gallery’s opening night celebration leading Kelly to go in for the kill; Shane is feeling boxed in by Jenny; and Alice starts to feel like three is a crowd.

The Los Angeles Gay & Lesbian Center dance marathon is on; someone is moving to the Big Apple; rumors fly fast around the dance floor that Alice and Tasha may be in couple trouble; The HIT!’s Sunset Blvd makes a shocking revelation to Kit; and there’s a no-show at the bus station.

In the final episode of the series, what starts out as a celebration of friendship quickly ends in a web of betrayal and deceit; the girls find themselves in the slammer with Sergeant Duffy; and the investigation into ? ? death begins…