Grammy Gallagher shows up on a medical furlough and tries to track down a former meth lab protege that owes her money; Sheila plans Karen's wedding reception; Fiona double dates with Steve and his Brazilian girlfriend, and discovers that Steve is married; Ethel reacts to Clyde's death; Frank discovers the identity of Eddie's insurance beneficiary.

Lip tries to get back in Karen's good graces by crafting a prenuptial agreement for her and Jody, while Ian continues to give Lip the silent treatment; Frank wants to kick Grammy out but Fiona resists until the basement meth lab explodes; Fiona is invited on a boat trip but doesn't realize Steve and his girlfriend are also attending.

With Grammy near death, Frank exits the house but walks in on Ian and Mickey locked in passion at the Kash and Grab; when Lip drops out of school, Fiona proposes a deal where they both earn their diplomas, but Lip acts out and gets himself expelled when he realizes that Karen plans to sell their baby to the highest bidder.

Monica returns to party and plot scams with Frank, but the rest of the family suspects she hasn't returned to stay; Fiona reconsiders her decision to kick Lip out of the house; Grammy's death affects everyone differently, and leaves Frank determined to make sure he gets every last penny his mother left behind; Sheila and Jody think Eddie's ghost is haunting the house.

Fiona starts to plan for her future now that Monica is back but her reprieve may be short-lived as Monica falls apart, spends the squirrel fund and gets arrested; Steve conspires to reunite Estefania with her true love so that he can be with Fiona; Lip and Ian learn the true identity of Mandy's baby; Sheila takes in a homeless crack addict.

It's a typical Gallagher nontraditional Thanksgiving that includes a suicide attempt by Monica, Carl shooting a bald eagle, and Karen going into labor; Steve agrees to allow Estefania's boyfriend to steal his identity; Ian sleeps with a businessman named Ned; Frank tries to get his share of his mother's money from his brother Clayton.

A lonely Frank schemes to break Monica out of the psychiatric facility. Jimmy earns his way back into Fiona's good graces and she asks to meet his family while Ian runs into Ned again.

Frank wakes up in a place completely foreign to him.

Fiona is stressed about the money she used for her club night; Frank makes his way home.

Frank tells Carl he has cancer to scam a charity foundation; Lip hunts down pedophiles in the neighborhood.

The city of Chicago gives notice that they're doing work on the sewer main. The problem? Aunt Ginger's bones are still buried in the yard and Frank needs to find her before the city does. Meanwhile, Fiona is picked on at work for not satisfying her boss. When Fiona fails to provide the support Jimmy needs, he turns to Este. Molly learns that she's a boy and Ned asks Ian to rob his wife's house.

Frank and Fiona go to extreme lengths in court to claim custody of the kids.

Fiona takes the kids on a camping trip. Essentially homeless, Frank seeks out Carl who sneaks him into the Gallagher van for the night.