12 Corazones is a Spanish-language dating game show produced in the United States for the television network Telemundo since January 2005, based on its namesake Argentine TV show format The show is filmed in Los Angeles and revolves around the twelve Zodiac signs that identify each contestant. The show is hosted by Penelope Menchaca and features advice from co-host Maximiliano Palacio, an Argentine former polo player turned actor, and Edward'O, an astrologist; Palacio and Edward'O often appear alternately in some episodes and simultaneously in others.

In August 2009, Telemundo added English subtitles as closed captions on CC3, airing on mun2 in that format.