A mass breakout occurs at each of the four supervillain prisons.

Ant-Man/Giant-Man, Hulk, Iron Man, Thor and Wasp band together to battle Graviton after he escapes from the Raft and targets Nick Fury.

While playing host to the Fantastic Four at Avengers Mansion, the Avengers find themselves under attack by Doctor Doom's forces.

A Skrull team posing as The Avengers invades Wakanda with only Ms. Marvel able to help the Black Panther.

The Skrull Empire initiates their seizure of Earth and the Avengers are hard pressed to thwart it.

With Captain America's reputation now in tatters, the superhero and the similarly maligned Spider-Man find themselves trying to thwart a prisoner transport interception.

When Henry Pym is apparently killed, a new vigilante using equipment broadly similar to the scientist's is discovered attacking criminals.

After a month of being dormant for repairs, The Vision finds the world under the control of Tony Stark.

While dealing with the Red Skull's escape with his Sleeper robots, Captain America also investigates the villain's former henchman who seems disturbingly familiar.

The Avengers and his allies face the ultimate test when Galactus, the Devourer of Planets comes to consume Earth.