Santo, Sam and Ed's Cup Fever! was an association football themed comedy television show in Australia on SBS. The nightly panel-style show was produced by Working Dog Productions and aired for the duration of the 2010 FIFA World Cup. The show was hosted by Santo Cilauro, Sam Pang and Ed Kavalee, with Rob Sitch making several guest appearances. Segments included Cup Update, an interview with a special guest and various comedy sketches.

Socceroos midfielder Mark Bresciano featured in his own diary segment. He also announced that he had signed for Serie A club Lazio during an interview on the show. Other regular segments included ‘Take on my Nuts’, ‘Not Even Close’ and ‘The Rivaldo Award’ which poked fun at World Cup proceedings and football in general. The show also had segments filmed at the World Cup by correspondent Tony Wilson.

The show was well received by viewers and has a thriving Facebook community. Due to the show's popularity, fans are pushing for the show to continue in some form since completion of the 2010 FIFA World Cup. The spin-off show Santo, Sam and Ed’s Sports Fever! was picked up by the Seven Network and began airing from January 2012.