McGarrett and Five-0 are captured and face certain death after tracking a dangerous nemesis to the Island of Lanai. Also, Grover takes his son to Chicago where he testifies against a dirty cop from his past.

Five-0 enlists the help of an old friend when the boss of a major crime family is murdered, triggering revenge killings across the island. Also, MacGarrett and Danny begin sorting out particulars in their new restaurant venture,

When an FBI agent who was cracking down on organized crime is killed, McGarrett rounds up every gang-related criminal on the island to find the culprit. Also, McGarrett tasks Adam with forming a new division within Five-0 to take on organized crime.

Harry Langford enlists McGarrett and Danny's help to track down Lady Sophie, a teenage British royal who has run away while under his protection. Also, Grover, Tani and Junior work a 25-year-old murder case after a mysterious Betamax tape arrives at 5-0 headquarters.

When a vacationing dad on a flight to Honolulu is kidnapped and force to parachute mid-flight, Danny, Tani and Junior track him through the jungle to discover that he may not be who he seems. Also, McGarrett is threatened with a secret from his past.

Tani and Junior go undercover at a gym to track down a deadly batch of steroids that’s killing users, before the drugs claim any more victims. Also, Danny and MacGarrett sub as bodyguards for Danny’s high maintenance ex-mother-in-law, Amanda Savage, a wildly famous romance novelist with whom he has never gotten along.

Five-0 continues to hunt down escaped criminal Aaron Wright before he can sell cyber-weapons to the highest bidder. Also, the lives of McGarrett and the team are put in danger when a visitor comes to headquarters to make amends.