Five-0 must work with rogue MI-6 agent Harry Langford to find a terrorist planning to cause nuclear reactors across Europe to meltdown. Also, McGarrett and Danny ask retired FBI profiler Alicia Brown to help them find their serial killer vigilante.

Five-0 enlists the help of an old friend when the boss of a major crime family is murdered, triggering revenge killings across the island. Also, MacGarrett and Danny begin sorting out particulars in their new restaurant venture,

Harry Langford enlists McGarrett and Danny's help to track down Lady Sophie, a teenage British royal who has run away while under his protection. Also, Grover, Tani and Junior work a 25-year-old murder case after a mysterious Betamax tape arrives at 5-0 headquarters.

Steve and Catherine are still reeling from the murder of one of their ohana and, along with Danny, Junior and some old friends, Harry Langford and Wade Gutches, hunt down the killer. Also, Tani and Grover investigate when a bag of human bones, discovered inside an abandoned storage locker, goes missing.

Harry Langford helps Five-0 investigate a series of murders that follow the plot of a fabled unpublished crime novel from the 1920s. Also, Tani and Junior's friendship takes a meaningful new turn.