A female jogger is found dead in Schuylkill River and Megan teams up with medical investigator Peter Dunlop to investigate her whereabouts before her murder. Meanwhile, Megan spends the day trying to solve a personal problem concerning her daughter's birthday.

A father is found stabbed to death in his home in the Philadelphia suburbs; Kate takes a consulting role in a case with Megan's ex-husband.

Megan suspects foul play when a young philanthropic socialite dies; the investigation is interrupted by Kate's personal life.

The investigation into a fatal car crash reveals the seedy underbelly of a perfect-looking neighborhood.

A champion equestrian is killed and potential drug use is suspected, but when Megan's daughter, who also rides, overhears details of the case, she leads the team to a clue and possibly the murderer.

When a popular 17-year-old high school student is found dead after a rave, the team must decipher various unknown drugs in his system and multiple bruises to figure out the cause of death. Meanwhile, Meghan is finally starting to date again after the divorce, but her ex-husband springs some shocking news on her and her daughter, causing tension at home.

A pharmaceutical rep is found dead in the Schuykill River, but when Megan Hunt and the team investigate, there's no blood found in her body. The team must locate the original crime scene to see if they can find the cause of death, but with suspects who have access to hundreds of unknown drugs, they may never know who or what killed her.

The parents of a seemingly perfect family are murdered; Curtis grapples with his new position; Megan's romantic life heats up.