A new investigation is opened up after a man assumed to be dead disappears off Ethan's exam table. When another body is found, it's the DNA evidence that leads to an eye-opening discovery.

A pharmaceutical rep is found dead in the Schuykill River, but when Megan Hunt and the team investigate, there's no blood found in her body. The team must locate the original crime scene to see if they can find the cause of death, but with suspects who have access to hundreds of unknown drugs, they may never know who or what killed her.

A murdered young woman's body turns up in place of a medical school cadaver during class, leaving Megan to rely on the aid of the star student to help solve the case.

When a recent lottery winner is found brutally murdered, everyone becomes a suspect.

Megan investigates the death of a bride on her wedding day; Ethan has a crush on the new girl, but she is interested in someone else.

When the owner of a family owned and operated Italian restaurant turns up dead in the freezer, Dr. Hunt and the team take a closer look into family matters. Meanwhile, Peter must face his own haunted past.

When two young girls are in a tragic car accident, one is left in critical condition and the other is found dead at the scene. As Megan and her team investigate the case, however, they realize there has been an awful mistake. Not only was the wrong girl pronounced dead, but the car accident may not have been the actual cause of death.

When a city-wide outbreak of a mysterious and lethal virus occurs, even Megan and her team are at risk. In order to determine who and what caused this outbreak, CDC Officer Charlie Stafford takes over the investigation.

The team needs to quickly figure out how to treat the virus when more and more people are becoming ill and dying.