Die Elrics treffen Shou Tucker, der Ed und Al viel über Alchemie – und auch über die furchtbare Grausamkeit, die manchmal mit ihr einhergeht – beibringen kann.

Edward und Alphonse werden von Scar angegriffen, einem mysteriösen und unglaublich mächtigen Mörder, der bereits wegen etlicher grausamer Meucheleien gesucht wird.

Da sie die schrecklichen Zutaten des Steins der Weisen nun kennen, durchsuchen die Elrics auf der Suche nach weiteren Informationen ein geheimes Labor.

Als Al von Chimären entführt wird und Eds Rettungsversuche fehlschlagen, beweist Izumi einmal mehr, dass ihr das Wohl der Brüder am Herzen liegt.

After learning of Hughes's fate, Ed and Al are ravaged by sadness and guilt. Envy still hides in plain sight among the State Alchemists, and another Homunculus is on the verge of infiltrating their ranks as well.

Ed's journey to a distant land of legend offers surprising new details behind Mustang's alleyway encounter with Ross. After a fateful encounter of his own, Elric learns a stunning secret about Winry's parents.

Mustang, Alphonse, Havoc, and Hawkeye split up to search a military laboratory. If Lust has her way, none of them will ever see each other alive again.

Hoping to learn more about the Homunculi, Ed and Al devise a risky strategy to lure the creatures out of hiding. Step one of the brothers' plan: risk death at the hands of their most dangerous enemy - Scar.

Even as his subordinates are scattered, Mustang finds he still has allies - unfortunately, so do his enemies. The Homunculi unleash one of the Ishvalan War's most notorious killers to deal with Scar and Marcoh.

Quiet warnings spread near and far: the Promised Day is at hand. While most will face the coming chaos with their own kind, Edward forms a new cabal comprised of human, chimera - and Homunculus.

Mustang leads a ragtag assault force of hardy northern troops - and welcome faces from the past - against Central's defenses. Victory seems certain until the military's most horrifying secret is revealed.

As one shared journey ends, many journeys begin. Those most touched by the conflict which surrounded the Philosopher's Stone now go their separate ways. One thing is certain: they will meet again.