Kakashi splits the two teams into five separate groups, each aided by a couple of his ninja dogs, in order to locate clues about Itachi and Sasuke's whereabouts. Unbeknownst to everyone, familiar foes have set their eyes upon both Naruto's group and Sasuke.

The power of the reanimated Madara Uchiha far exceeds what the Allied Forces expected. Despite the difference in power, the Third Tsuchikage, Ohnoki, along with Naruto and Gaara, refuses to give up.

Sasuke begins his own investigation into the incidents. He overcomes many dangers on his path to the truth. The Exploding Humans, the Ketsuryugan, the Chinoike Clan, and the Uchiha Clan—just how are they connected? Where does his journey lead? The mystery is about to be solved...