When two lovable pups are dropped off at Villalobos' dog boutique, the VRC crew is determined to get them back to good health. Then, a young woman comes in searching for a canine perfect to experience the Big Easy lifestyle with her.

Tia and Earl face a decision about an elderly hound needing medical attention at an Alabama shelter; an abandoned, aggressive dog is found roaming a trash-filled backyard.

Tia takes in a pit bull that was rescued from terrible conditions in Kuwait; an adopter travels from Michigan in hopes of finding a new best friend; when a stray dog ends up at Villalobos, Earl is determined to track down its owner.

When Kenani is in a serious motorcycle accident, Tia and the Villalobos crew must band together to ensure him a speedy recovery; a retired Marine visits the center to find a forever fur-friend; Lizzy and Earl rescue a hound found in a parking lot.

Tia races to a rural shelter in Louisiana to rescue four dogs from euthanasia. Meanwhile, Mariah and Toney give a scared, shy dog a shot at a forever home, and a unique canine gets a chance at a dog program in a Pennsylvania prison.

Toney and Earl rescue an aggressive dog that is found tied up in front of an abandoned home; Mariah helps a deserted canine that is struggling with neurological issues.

Mariah looks for a homeless woman needing to give up her beloved pit bull. Meanwhile, Lizzy prepares her favourite rescue for a home after dealing with his medical issues.

Tia and M2 welcome back a couple who want to reunite their adoptee with her former best friend. Mariah and Toney discover a hound in desperate shape, while Mariah does everything in her power to nurse VRC's first Louisiana rescue back to health.