The Enterprise, under Captain Jonathan Archer, sets off on its maiden voyage with a mission to return a wounded Klingon to his people.

In a Klingon tribunal, Archer stands accused of aiding fugitives of the Empire and faces death if found guilty.

While dissension among Xindi ranks festers, Enterprise tries to recover from a devastating attack.

In the mirror universe, Commander Archer mutinies against Captain Forrest in order to capture a future Earth ship found in Tholian space.