Scott Bakula starts off with a discussion on the third season story arc, the Xindi Saga, and how that pushes the series and the development of the characters in it. Phyllis Strong, André Bormanis, Mike Sussman, David A. Goodman. Brannon Braga, Rick Berman. Chris Black & David Livingston talked about the influences of the 9/11 tragedy on this story arc. There was also pressure to make the show more "edgy" and the lack of a complete roadmap for the story arc when the season started. Manny Coto talks about how he influenced the arc through the season and satisfied Brannon Braga's desire for the right alchemy in the writer's room.

Rick Berman talks about the job of orchestrating Star Trek from The Next Generation through Enterprise. The production crew and the Enterprise cast comment on the end of the era.