When Trip is dispatched to assist a Xyrillian ship with its power source problems, he is delighted to have a friendly encounter with one of the ship's female engineers. However, shortly after returning to Enterprise, he discovers that their seemingly innocuous interaction has led to a surprising result.

In need of fuel, the Enterprise arrives at a Quonset mining colony for deuterium supplies. They discover that Klingons are forcing the colonists to give up all their deuterium. Archer and the rest of the crew work to train the colonists so they can fight back against the Klingons.

The NX-01 gets closer to a showdown with the Xindi when Captain Archer takes on an enigmatic passenger: a beautiful slave named Rajiin.

Archer, Reed and Major Hayes infiltrate a Xindi-Sloth industrial colony to learn more about the weapon of mass destruction that will be used against Earth.

The fate of Enterprise is in Dr. Phlox's hands as the rest of the crew must be induced into a coma in order to survive a trans-dimensional disturbance.

While dissension among Xindi ranks festers, Enterprise tries to recover from a devastating attack.

Archer and Hoshi stand before the Xindi Council as T'Pol and Reed lead a team into the heart of a Sphere.

Arik Soong leads his band of Augments to a medical facility where hundreds of genetically enhanced embryos are still stored, intending to retrieve them and bring them to life.

Archer and T'Pol encounter the Syrrannites, a radical group hiding in the Vulcan desert, while the NX-01 crew contends with Vulcan power ploys.

Non corporeal aliens study the Enterprise crew as they respond to a fatal viral infection brought on board from an away mission.

Archer visits Shran's icy homeworld to find an Andorian subspecies called the Aenar, to determine their connection to the marauder destroying ships in the region.

As a gift for negotiating with the Orion Syndicate, Captain Archer receives three Orion Slave Girls.

A xenophobic faction of humanity threatens to undermine talks to form a new coalition of planets.