Sheridan is shocked to learn that one of the crew of the Icarus, a science ship that exploded with his wife aboard, is alive - namely Mr. Morden. A representative of the Ministry of Peace comes to the station to recruit personnel to the Nightwatch.

The new Centauri appointed Narn government send a replacement for G'Kar, while an alien probe threatens to destroy Babylon 5 unless it gets the answers for a series of complicated scientific questions.

Bester comes to the station to track down a dealer of Dust - an illegal drug that gives normal people temporary telepathic powers. G'Kar is also interested in the drug. He sees it as a potential weapon against the Centauri, but first he has to test it.

The renegade destroyer "Alexander" arrives at Babylon 5 and Sheridan is forced to announce the station's secession from the Earth Alliance, and prepare for an attack by Clark's forces. Meanwhile, Delenn is forced to go to Minbar when the Grey Council refuses to act upon increased Shadow activity.

Londo forces Vir to participate in a plan to kill G'Kar. Sheridan struggles with figuring out the Shadows' tactics.

In the aftermath of the explosion on Z'ha'dum, Sheridan is presumed dead and Garibaldi is missing. Delenn struggles to keep the alliance against the Shadows together, and Londo takes up his new position on Centauri Prime as security advisor to the emperor.

With the Vorlons destroying whole worlds, Babylon 5 is struggling to cope with the refugees. And with one Vorlon aboard, they cannot make a move without them knowing about it, so Sheridan decides to kill him. On Centauri Prime, Cartagia explains to Londo how he will become a god when the Vorlons destroy the planet.

Garibaldi gets his first assignment from his new employer - helping someone getting on and off the station without having to pass through customs. He is quite surprised at who this person is. Meanwhile, Ivanova makes preparations for the first broadcast of "The Voice of the Resistance".

Garibaldi is barely able to convince Lyta and Franklin that his recent behavior was caused by Bester, and they organize a rescue for Sheridan. Meanwhile, Ivanova gets word that a trap has been set at the fleet's next rendezvous point by a group of completely new advanced-technology destroyers.

Londo collapses from a heart attack, and must battle with his guilt in a dream state. Delenn learns that Lennier is planing to leave Babylon 5 to join the Rangers.

Four rangers come from Minbar with a status report to Delenn, while a Downbelow racketeer decides it's time to get rid of Zack.

Londo starts to suspect that all is not right on Centauri Prime, when a good friend is murdered. On Babylon 5, Byron tries to force the council to give him and his telepaths a homeworld of their own.

More bloodhound units arrive and the fight with the violent faction of Byron's followers intensifies until the rogues seize Medlab - with Garibaldi and Franklin in it.