Black Jack accepts a three million dollar fee from the young and beautiful Sayuri Crossword to treat Manabis Crossword (the Chairman of the Carosan Corporation and Sayuri's husband) on isolated windswept Raoski Island. Black Jack arrives to find a frail old man, wracked with painful spasms as all the water drains from his body leaving him weak from dehydration. Eighty doctors could find no cause, but Jack discovers that he has Kimaira, a disease endemic to the island and supposedly dormant for 150 years. However it actually surfaced 60 years earlier, infecting the Crossword family who were all killed by the villagers except the young Manabis. Manabis asks Black Jack to operate on him during a spasm to find the cause of the disease. Black Jack agrees and discovers that the Kimaira virus just as Manabis dies enabling a cure to be developed.