A lady flasher enlivens the halls and rooms of St. Eligius; Fiscus moves in with Ehrlich; Cavanero faces a difficult choice about a fellowship; Dr. Auschlander's cancer remission appears to be ending; Morrison and Chandler try to help a young man injured in a street beating whose brother is determined to get revenge.

A pushy, abrasive man literally drives into the E.R. to get help for his wife; Ehrlich finds an unusual girlfriend at the laundromat; Fiscus loses both Cathy and Shirley; Dr. Craig clashes with the newly appointed city comptroller, Joan Halloran, over his proposed heart transplant for schoolteacher Eve Leighton.

Medical student Elliot Axelrod and plastic surgeon Dr. Bobby Caldwell join the staff; Eve Leighton's sister expresses reservations about the planned transplant; a resident dropped from the hospital program badgers Cavanero to reevaluate him; and Dr. Craig enlists Dr. Caldwell's help in opposing Joan Halloran's plan to shut down an outpatient surgery clinic.

Dr. Auschlander suggests a controversial liver dialysis procedure for Wegener's little girl, using her father's liver to do the work; Cavanero is stung by the same rumor she started about Dr. Holtz; and Chandler reports an old voodoo woman for practicing medicine without a license. Dr. Craig is called before the fees commission. Rosenthal meets Clarendon's wife.

Mrs. Auschlander faces major heart surgery; Dr. Craig is disturbed to see the ravages of time on his mentor, Dr. David Domedion; Ehrlich searches for a religion; the messiah shows up for a Celtics game; and Dr. Westphall announces his resignation at a friendly little bar called Cheers.