King Henry marries for the third time, taking as his queen the demure noblewoman Jane Seymour. A growing number of his subjects protest the king's decision to abandon the Catholic Church.

The uproar over the king's break with the Catholic Church turns into a full-blown rebellion that comes to be known as "The Pilgrimage of Grace." Immobilized by an old jousting injury, Henry sends Charles Brandon to deal with the uprising and focuses his attention on the Lady Ursula Misseldon.